Can We Outsmart Cancer?
Millions face cancer diagnoses every year. Outsmarting cancer demands more, not only medical expertise but also engineering and technological innovation. With this combination, EnMed researchers are developing new diagnostic approaches that can detect cancer early and more reliably, understand how cancer develops, and develop new therapeutic approaches to target aggressive cancers.
Pioneering Cancer Discoveries
A New Marker of Cancer
New research shows that cancer cells often develop unusual “wrinkles” in the nucleus—the center of the cell where genetic information is stored. While these wrinkles are hard to see with traditional lab tests, advanced imaging and computer technology can uncover them. Identifying these nuclear wrinkles could provide doctors with a new, more precise way to detect and diagnose cancer, offering hope for earlier treatment and better outcomes.
Learn MoreFaculty
Jason George, PhD, MD
Texas A&M College of Engineering
Biana Godin, MScPharm, PhD
Houston Methodist
Tanmay Lele, PhD
Texas A&M School of Engineering Medicine
Hui-Wen Lo, PhD, MA, MS
Texas A&M University
Raksha Raghunathan, PhD
Houston Methodist
Jiho Shin, PhD
Texas A&M College of Engineering
Stephen Wong, PhD
Houston Methodist
Hong Zhao, MD, PhD
Houston Methodist
Yubin Zhou, MD, PhD, FAIMBE, FRSC
Texas A&M UniversityPublications and Grants
Our interdisciplinary research brings together clinical expertise and cutting-edge engineering to transform cancer research and care. We are committed to creating tangible improvements for patients and making a positive impact on the broader healthcare community.
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Cells often need to move through narrow spaces, whether during healing or when cancer spreads. But squeezing their large, bulky nuclei through tight gaps seemed almost impossible—until now. Scientists have discovered that the surface of the cell’s nucleus has extra “wrinkles,” allowing it to change shape and pass through tiny constrictions without damaging its contents. This new understanding of nuclear flexibility could offer insights into cancer invasiveness and how our bodies heal.